IBS & Gut–Brain Axis

Purpose: Irritable Bowel Syndrome (IBS) represents one of the largest and most commercially significant segments within functional gastroenterology, with the gut–brain axis playing a central role in symptom development and management. Increasing recognition of the interaction between gastrointestinal function, stress, mood, and the nervous system has driven demand for integrated IBS care models.

Keynote Points:

  • High global prevalence and chronic nature of IBS

  • Growing focus on gut–brain signaling and neurogastroenterology

  • Demand for neuromodulators, probiotics, and microbiome-based therapies

  • Expansion of digital therapeutics, CBT-based apps, and virtual care

  • Strong market for dietary interventions and personalized nutrition

  • Rising patient acceptance of integrative and holistic IBS management

  • Collaboration opportunities across GI, mental health, and digital health

Benefits:

  • Large, recurring patient population with long-term care needs

  • Multiple revenue streams across pharma, wellness, nutrition, and digital platforms

  • High patient engagement supporting subscription and program-based models

  • Strong differentiation through integrated gut–brain care solutions

  • Attractive ROI aligned with chronic disease management

  • Positions brands at the forefront of next-generation functional GI care